In brief
- A combined wrinkle treatment brings together PRP and hyaluronic acid, and sometimes also botulinum toxin for expression lines.
- PRP is based on the patient's own plasma and stimulates collagen production and skin renewal.
- Hyaluronic acid restores lost volume and visibly smooths deep wrinkles immediately.
- The combination improves skin quality from within alongside immediate smoothing and added volume.
- At Dermacare, treatments are performed by expert doctors, and a minor touch-up, if needed, is included free of charge for up to three weeks.
A combined wrinkle treatment smooths wrinkles, improves skin quality and restores your natural glow without looking artificial – the dream of many who choose aesthetic treatments. But which method is the most suitable? At the Dermacare clinic in Petah Tikva, the answer is often not "either/or" but "both". Combining PRP (platelet-rich plasma) and hyaluronic acid creates a particularly powerful effect – for smooth, youthful skin.
PRP – natural skin rejuvenation
PRP is based on the patient's own blood. How does it work? A small amount of blood is taken from the patient. The blood is centrifuged to separate its components until platelet-rich plasma is obtained, which is injected back into the skin in the treatment area. This plasma contains a high concentration of growth factors that encourage the skin to renew itself.

The treatment activates collagen production, cell renewal and improved blood circulation – ideal for preventing sagging skin, smoothing wrinkles and treating scars. The treatment is natural and contains no foreign substances. It is particularly suitable for sensitive skin or for those who prefer natural methods.
PRP is recommended for those with tired or dull skin, pigmentation spots, scars or wrinkles. The treatment is also effective for acne scars and for improving skin structure.
Wrinkle treatment with hyaluronic acid – targeted treatment with an immediate effect
Treatment with hyaluronic acid delivers immediately visible results. Hyaluronic acid is a natural component of the skin that declines over the years, leading to a loss of volume, elasticity and moisture in the skin.

Precise injections of high-quality hyaluronic acid restore lost volume, smooth wrinkles and harmoniously contour facial features. The treatment is especially popular for deep wrinkles such as nasolabial folds and marionette lines, or for shaping the lips and cheeks.
Where signs of ageing are pronounced, this treatment visibly firms the skin – without recovery time or surgery.
Combined wrinkle treatment – the winning combination?
The real power is revealed in the combination of PRP and hyaluronic acid. While PRP strengthens skin quality from within, hyaluronic acid provides immediate smoothing and added volume. This synergy creates natural, fresh and vibrant results, without an artificial look.
In some cases, botulinum toxin (Botox) can also be added to relax expression lines on the forehead, around the eyes or on the chin. We at the Dermacare clinic are leaders in skin rejuvenation treatments with hyaluronic acid and other proven methods. Our team of expert doctors ensures a personalised approach based on your skin type, age and goals.
Why the Dermacare clinic?
For those interested in skin rejuvenation treatments, the Dermacare clinic offers not only a combination of modern treatments, but also medical expertise of the highest standard. Treatments are performed only by expert doctors who specialise in aesthetic procedures. Whether it is PRP, hyaluronic acid or Botox – all products are tested and proven.
Another advantage: if a minor touch-up is needed after treatment, it is included free of charge for up to three weeks from the date of treatment. You will also enjoy fair prices, excellent accessibility and comprehensive support.
Natural results
Modern aesthetics does not require choosing between methods, but rather combining them in a targeted way. The combination of PRP and hyaluronic acid creates a perfect balance between renewal and volume, tailored to your personal needs. This is a combined wrinkle treatment that gives a natural, youthful look over time.
Book a personal consultation at the Dermacare clinic in Petah Tikva and discover the benefits of a combined wrinkle treatment for smoother, fresher and more natural skin. Contact us by phone on 03-6127888 or by email at info@dermacare.co.il.
Frequently asked questions
Hyaluronic acid-based fillers are particularly suitable for treating expression lines around the nose and mouth (nasolabial folds), marionette lines, hollow cheeks, hollows under the eyes (tear trough contouring) and the jawline. In addition, hyaluronic acid is also used to contour the chin, add volume to the lips and rejuvenate the skin of the neck and décolletage. At Dermacare clinic, hyaluronic acid is combined in particular in the vampire facial (PRP), in which platelet-rich plasma is injected together with hyaluronic acid. This treatment helps to smooth, tighten and renew the skin for a young, fresh look.
Hyaluronic acid is a natural substance found in the body. Chemically, it is a chain of sugar molecules with a very high capacity to absorb and retain water. In anti-aging, hyaluronic acid is used to treat wrinkles because of its ability to bind an amount of water 6,000 times its own weight – that is, one gram of hyaluronic acid can absorb up to 6 litres of water. In the human body, most hyaluronic acid is found in the skin, where it helps hold the cells together and keeps the skin moisturised. It is also found in the joints and the eyes.
From the age of 25, the body produces less hyaluronic acid, and by the age of 60 only about 10% of the original reserve remains in the body.
Botox is a liquid protein that relaxes, in a targeted way, the muscles that cause wrinkles to form. As a result, the wrinkles are reduced. The substance is injected directly into the muscle that causes the wrinkle. The effect lasts between 4 and 6 months.
Hyaluronic acid is a natural, gel-like substance that is injected into or under the skin. Thanks to its ability to bind water, the substance adds volume to the tissue, and so helps reduce wrinkles or smooth the skin. Depending on the product used, hyaluronic acid is broken down by the body over 9 to 24 months.
Hyaluronic acid injections work by creating a filling effect and adding volume to the treated area. In addition, hyaluronic acid binds fluids, which improves moisture levels in the skin and lips, giving them a fresh, full and vibrant look.











